C-reactive protein in the serial assessment of disease activity in rheumatoid arthritis
| Autor: | V. Wright, N. G. Sitton, Howard A. Bird, J. S. Dixon, M. E. Pickup |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
musculoskeletal diseases
Adult Male medicine.medical_specialty Immunology Azathioprine Fibrinogen Gastroenterology Arthritis Rheumatoid Rheumatology Internal medicine medicine Immunology and Allergy Humans skin and connective tissue diseases Aged Aspirin biology business.industry C-reactive protein Haptoglobin Hydroxychloroquine General Medicine Blood Proteins Alclofenac Middle Aged medicine.disease Surgery C-Reactive Protein Rheumatoid arthritis biology.protein Female business medicine.drug Acute-Phase Proteins |
| Zdroj: | Scandinavian journal of rheumatology. 13(1) |
| ISSN: | 0300-9742 |
| Popis: | C-reactive protein (CRP) levels were measured in 105 patients with rheumatoid arhtiritis (RA) during treatment with slow-acting anti-rheumatoid drugs D-penicillamine, alclofenac, hydroxychloroquine, gold, sulphasalazine and azathioprine. A control group treated with aspirin alone was also included. Patients were assessed clinically (pain score, articular index and summated change score) and in terms of acute-phase reactants (CRP, haptoglo-bin, fibrinogen, ESR and plasma viscosity) at eight separate clinic visits during the 6-month treatment period. The estimation of CRP was found to be more useful than haptoglobin, fibrinogen or ESR as an index of disease activity. |
| Databáze: | OpenAIRE |
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