The mechanisms of hydrolysis of glycosides and their revelance to enzyme-catalysed reactions
| Autor: | Vernon Ca |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
chemistry.chemical_classification
Chemical Phenomena Chemistry Stereochemistry Aryl General Engineering Ketose Glycoside Models Theoretical Carbohydrate Catalysis Hydrolysis chemistry.chemical_compound Aldose General Earth and Planetary Sciences Glycosides Glycolysis Alkyl General Environmental Science |
| Zdroj: | Proceedings of the Royal Society of London. Series B. Biological Sciences. 167:389-401 |
| ISSN: | 2053-9193 0080-4649 |
| DOI: | 10.1098/rspb.1967.0036 |
| Popis: | Glycoside hydrolysis can be formally represented by (I). where the group O R ( R is alkyl, aryl or a carbohydrate) is displaced from the C 1 or C 2 atom of an aldose or ketose sugar (or sugar derivative) respectively; the ring system being either five- or six-membered. Like the analogous hydrolysis of acetals, glycoside hydrolysis shows specific catalysis by hydrogen ions and, except where R is an aryl residue, base catalysis is absent. A number of enzymes* catalysing the hydrolysis of particular glycosides have been characterized: all show a high degree of specificity towards the carbohydrate structures present in the substrates. Both the acid-catalysed and the enzyme-catalysed reactions have been much studied, but whereas the former are now reasonably well understood, the mechanisms involved in the latter are still largely unknown. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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