Carbamylated Haemoglobin in Normal, Diabetic and Uraemic Patients
| Autor: | Jonathan T. C. Kwan, Michael R. Bending, J L Barron, Edwin C Carr |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Male 030213 general clinical medicine medicine.medical_specialty Clinical Biochemistry 030209 endocrinology & metabolism Haemoglobin levels Gastroenterology Hemoglobins 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus Diabetes Mellitus medicine Humans Urea Hospital patients Haemodialysis procedure Chromatography High Pressure Liquid Aged Uremia Chemistry Significant difference Healthy subjects General Medicine Middle Aged medicine.disease Biochemistry Creatinine Female Hemoglobin |
| Zdroj: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 29:206-209 |
| ISSN: | 1758-1001 0004-5632 |
| DOI: | 10.1177/000456329202900215 |
| Popis: | Carbamylated haemoglobin arises from the non-enzymic modification of haemoglobin monomers by isocyanate derived from the spontaneous dissociation of urea. We measured carbamylated haemoglobin by high performance liquid chromatography in healthy subjects, non-uraemic hospital patients, diabetics, and different groups of uraemic patients. Carbamylated haemoglobin levels were found to be raised in uraemic subjects, but were independent of age, sex, glycaemic state and haemodialysis procedure. There was no significant difference in carbamylated haemoglobin levels between two groups of patients having different modes of dialysis treatment, probably indicating a similar degree of uraemic exposure in these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|