The Influence of Dynamic Blood Viscosity on Coronary Blood Flow in Stenotic Artery
| Autor: | Demkin, V. P., Melnichuk, S. V., Zavadovskii, K. V., Khoryak, M. N., Rudenko, V. V., Suyundukova, A. T., Kukartseva, D. N., Tsibulina, A. O., Udut, Vladimir V. |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Russian physics journal. 2022. Vol. 64, № 12. P. 2364-2370 |
| ISSN: | 1573-9228 1064-8887 |
| DOI: | 10.1007/s11182-022-02598-1 |
| Popis: | The paper proposes the calculation technique for the coronary blood flow in stenotic arteries with respect to the blood viscosity affecting the parameters of the fractional flow reserve based on the data analysis of the multispectral computed tomography. The calculation technique is also based on regulations that determine the hemodynamics in stenotic vessels. The mathematical simulation is presented for the blood flow in a stenotic coronary artery. This simulation is based on the Navier-Stokes equations. The calculations are carried out using Comsol Multiphysics 4.2. software. The obtained results show that the distribution of the blood flow rate in the stenotic artery is not uniform, and the pressure out of the stenotic segment of the artery depends on the blood viscosity. This must be taken into consideration both in mathematical simulation and invasive coronary angiography of the fractional flow reserve. The research results can be used in effective diagnostics of coronary artery disease. |
| Databáze: | OpenAIRE |
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