A study of 3013 cases of hepatocellular carcinoma: Etiology and therapy before and during the current decade

Autor: Poh-Seng Tan, Terence C-W Huey, Miao-Shan Lim, Jason P-E Chang, J.K. Low, Alfred Wei Chieh Kow, Iyer G. Shridhar, Chee-Kiat Tan, George B-B Goh, Sameer P. Junnarkar, Vishalkumar G Shelat, Yock Young Dan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: JGH Open: An Open Access Journal of Gastroenterology and Hepatology
JGH Open, Vol 5, Iss 9, Pp 1015-1018 (2021)
ISSN: 2397-9070
Popis: Background and Aim Hepatocellular carcinoma (HCC) is a significant global problem. With advances in HCC diagnosis and therapy, our hypothesis is that there are significant differences in the clinical characteristics and treatment of HCC over the years. Methods Patients with HCC between 1980 and 2018 from three major tertiary hospitals in Singapore were enrolled into a Research Electronic Data Capture database. Clinical characteristics and treatment of HCC were compared between those diagnosed before 2008 (cohort A) and during the current decade (ie from 2008 onwards) (cohort B). Results There were 3013 patients. Mean age of HCC diagnosis was significantly older in cohort B (68.6 vs 61.2 years, P
This is a study of 3013 cases of hepatocellular carcinoma (HCC) from all the three tertiary hospitals in Singapore. It shows the changing trend of etiology of HCC over time with chronic hepatitis B infection decreasing in lieu of cryptogenic/non‐alcoholic steatohepatitis etiology. It also documents for the first time HCC treatment modality in Singapore and the change over time.
Databáze: OpenAIRE
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