Impact of Composition and Morphology of Ketoconazole-Loaded Solid Lipid Nanoparticles on Intestinal Permeation and Gastroplus-Based Prediction Studies

Autor:	Shaya Jubran Aljurbui, Afzal Hussain, Mohammad Yusuf, Mohhammad Ramzan, Obaid Afzal, Basmah Almohaywi, Sabina Yasmin, Abdulmalik Saleh Alfawaz Altamimi
Rok vydání:	2022
Předmět:	General Chemical Engineering General Chemistry
Zdroj:	ACS omega. 7(26)
ISSN:	2470-1343
Popis:	Ketoconazole (KTZ) is a potential oral antifungal agent to control systemic and local infections. This study addresses the impact of composition (tween 80 and compritol as CATO) and morphology on permeation (stomach, jejunum, and ileum) profiles of KTZ-loaded solid lipid nanoparticles (SLNs) in rats followed by
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28b870a5bbc9343f207b344f03a3310 https://pubmed.ncbi.nlm.nih.gov/35811933 Zobrazit plný text záznamu