The Qualitative and Quantitative Structure of Oral Microbiocenosis in Rats with Periodontitis in a Setting of Hyper- and Hypothyroidism
| Autor: | Inna Krynytska, V. V. Shcherba, Mariya Marushchak, M. M. Korda |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Periodontitis Flora business.industry Specialties of internal medicine Physiology Quantitative structure 030206 dentistry medicine.disease Hard tissue Highly sensitive 03 medical and health sciences 030104 developmental biology 0302 clinical medicine RC581-951 Thyroid dysfunction microbiocenosis medicine Endocrinology diabetology thyroid alterations business periodontitis Dysbiosis |
| Zdroj: | Romanian Journal of Diabetes Nutrition and Metabolic Diseases, Vol 26, Iss 3, Pp 293-304 (2019) |
| ISSN: | 2284-6417 |
| DOI: | 10.2478/rjdnmd-2019-0030 |
| Popis: | Background and aims. Oral microbial flora is a highly sensitive indicator system producing qualitative and quantitative responses to changes in various individual organs and systems. The aim of study was to perform a comparative analysis of qualitative and quantitative structure of oral microbiocenosis in rats with comorbidity-free periodontitis and in animals with periodontitis in a setting of hyper- and hypothyroidism. Material and methods. Experimental studies were conducted on 48 mature male white rats. Samples for microbiological tests were taken from dental surfaces (on the border between hard tissue and gums in the interdental spaces). The isolated pure cultures were identified by their morphological, tinctorial, cultural and biochemical properties and the signs of pathogenecity. Results. We found that the oral dysbiosis occurring in a setting of periodontitis in rats is chiefly characterized by increased quantity of coccal forms and by increased candidal inoculation; these organisms cumulatively inhibit the growth of normal microbial flora, such as Lactobacilli, bacteroids and Bifidobacteria. Thyroid dysfunction exacerbates changes in the qualitative and quantitative structure of oral microbiocenosis. Conclusions. The periodontitis in a setting of thyroid dysfunction increases both the species variety and the quantitative counts of oral microbial flora, with predominance of such microbial organisms as Staph. aureus, E. coli, E. faecalis, Candida albicans and P. aeruginosa. |
| Databáze: | OpenAIRE |
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