Seroprevalence of pertussis amongst healthcare professionals in Spain

Autor: Pilar García-Corbeira, Raghavendra Devadiga, Monica Tafalla, Josep Maria Ramon Torrell, María Isabel Castro Lareo, Janet Reyes, Maria Luisa Rodriguez de la Pinta, Cynthia McCoig, Juan García de Lomas
Rok vydání: 2016
Předmět:
Adult
Male
0301 basic medicine
medicine.medical_specialty
Pediatrics
Whooping Cough
030106 microbiology
Seroprevalence
Enzyme-Linked Immunosorbent Assay
Pertussis antibodies
Young Adult
03 medical and health sciences
0302 clinical medicine
Seroepidemiologic Studies
Healthcare professionals
Immunology and Microbiology(all)
Health care
Prevalence
Humans
Medicine
030212 general & internal medicine
Young adult
Whooping cough
Aged
General Veterinary
General Immunology and Microbiology
Health professionals
business.industry
Public Health
Environmental and Occupational Health
Middle Aged
Serum samples
medicine.disease
Antibodies
Bacterial
veterinary(all)
Hospitals
humanities
Personnel
Hospital
Vaccination
Infectious Diseases
Spain
Family medicine
Molecular Medicine
Female
Observational study
business
Zdroj: Vaccine. 34:1109-1114
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2015.12.036
Popis: Introduction This multi-center, hospital-based observational study determined the seroprevalence of pertussis antibodies amongst healthcare professionals from three different hospitals in Spain to ascertain the health status of professionals attending to susceptible groups who are at risk of contracting and transmitting pertussis. Methods Medical professionals from three hospitals in Spain were recruited for this study ( NCT01706224 ). Serum samples from subjects were assessed for anti-pertussis antibodies by ELISA. The percentage of subjects positive for anti-pertussis antibodies were determined by age-strata, gender, vaccination status, professional level (physicians, nurses, ancillary nurses and midwives), hospital department, number of working years, numbers of hours spent with the patient as well as number of children in the household. Results Overall, 31.2% of subjects were seropositive; 3.3% of these healthcare professionals had ELISA values indicative of current or recent infection. There were no significant differences in terms of pertussis prevalence with respect to age, gender, hospital department, profession, number of working years and number of hours spent with patients. These levels of seronegativity amongst healthcare workers further strengthen the rationale for vaccination amongst this specific population against pertussis.
Databáze: OpenAIRE
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