Modified Glasgow Coma Scale Using Serum Factors as a Prognostic Model in Traumatic Brain Injury
| Autor: | In Suk Bae, Hyeong Joong Yi, Koang Hum Bak, Dong-Won Kim, Hyoung Joon Chun, Kyu Sun Choi |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Traumatic brain injury medicine.medical_treatment Logistic regression Hemoglobins Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine Brain Injuries Traumatic medicine Humans Glasgow Coma Scale Aged Cause of death Aged 80 and over Prothrombin time L-Lactate Dehydrogenase medicine.diagnostic_test Platelet Count business.industry Glasgow Outcome Scale Middle Aged Prognosis medicine.disease 030220 oncology & carcinogenesis Prothrombin Time Prognostic model Female Surgery Decompressive craniectomy Neurology (clinical) business Biomarkers 030217 neurology & neurosurgery |
| Zdroj: | World Neurosurgery. 126:e959-e964 |
| ISSN: | 1878-8750 |
| Popis: | Background Traumatic brain injury (TBI) is a major cause of death and disability. This study evaluated a possible relationship between serum factors at admission and the outcome of TBI. We propose a statistically validated scale for patients with TBI that combines serum factors and the Glasgow Coma Scale (GCS). Methods Between May 2011 and July 2016, 219 patients underwent decompressive craniectomy for TBI. We assessed laboratory data on admission, and correlations with GSC and Glasgow Outcome Scale were investigated. The modified GCS was developed from a multivariable logistic regression model, which was validated with the backward stepwise method. Results Of 219 patients with TBI enrolled in our study, 175 were men (79.9%) and 44 were women (20.1%) with a mean age of 49.1 ± 11.5 years. Initial serum values of hemoglobin, platelets, prothrombin time, and lactate dehydrogenase were associated with in-hospital mortality. The factor score was derived by adding the following points: hemoglobin (≥13.0 g/dL = 0, Conclusions The modified GCS score using serum factors extended the information provided about patient outcomes to be comparable to more complex methods. The modified GCS score may be useful to predict in-hospital mortality in patients with TBI. |
| Databáze: | OpenAIRE |
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