Outcomes and prognostic variables associated with primary abdominal visceral soft tissue sarcomas in dogs: A Veterinary Society of Surgical Oncology retrospective study
Autor: | Maninder Sandey, Whitney Smiley, Julius M. Liptak, Arathi Vinayak, Janet A. Grimes, Dan Linden, Brad M. Matz |
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Rok vydání: | 2019 |
Předmět: |
Male
Societies Scientific Leiomyosarcoma Prognostic variable medicine.medical_specialty 040301 veterinary sciences Soft Tissue Neoplasms Metastasis 0403 veterinary science 03 medical and health sciences Dogs 0302 clinical medicine medicine Animals Dog Diseases Grading (tumors) General Veterinary business.industry Soft tissue sarcoma Sarcoma Retrospective cohort study 04 agricultural and veterinary sciences medicine.disease Surgical Oncology Treatment Outcome Abdominal Neoplasms 030220 oncology & carcinogenesis Female Histopathology Radiology business |
Zdroj: | Veterinary and Comparative Oncology. 17:265-270 |
ISSN: | 1476-5829 1476-5810 |
Popis: | Primary abdominal visceral soft tissue sarcomas (STSs) are rare tumours in dogs with little information available on outcomes. The goal of this retrospective, multi-institutional study was to describe the common tumour types, location and prognostic factors associated with primary abdominal visceral STSs. Medical records were searched for dogs with primary abdominal visceral STSs at six institutions and were retrospectively reviewed. Tumours were graded using the previously described grading scheme for STSs of the skin and subcutis when information in the histopathology report contained adequate details. Forty-two dogs were included in the study. Five dogs had grade I tumours, 11 had grade II and 15 had grade III tumours. The most common tumour type was leiomyosarcoma (38.1%). The most common tumour locations were the spleen (47.6%) and small intestine (23.8%). The local recurrence rate was low (4.7%). Metastasis was present at the time of surgery in 23.8%, and the overall metastatic rate was 40.4%. Mitotic index of ≥9 was associated with significantly shorter survival time (MST 269 days) compared with a mitotic index of |
Databáze: | OpenAIRE |
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