Early identification of peripheral neuropathy based on sudomotor dysfunction in Mexican patients with type 2 diabetes
| Autor: | María Magdalena Rojas-Uribe, Adolfo Chávez-Negrete, Julián Alberto Hernández-Domínguez, Mario Molina-Ayala, Angélica Carbajal-Ramírez |
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| Rok vydání: | 2019 |
| Předmět: |
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medicine.medical_specialty Diabetic neuropathy Neurology Type 2 diabetes lcsh:RC346-429 Study Protocol 03 medical and health sciences 0302 clinical medicine Diabetic Neuropathies Surveys and Questionnaires Internal medicine Diabetes mellitus medicine Humans Neurochemistry 030212 general & internal medicine Mexico lcsh:Neurology. Diseases of the nervous system Aged Neurologic Examination business.industry Galvanic Skin Response General Medicine Middle Aged medicine.disease Electrochemical skin conductances Sudomotor Peripheral neuropathy Diabetes Mellitus Type 2 MNSI Cardiology Female Neurology (clinical) Neurosurgery business 030217 neurology & neurosurgery Small fiber neuropathies |
| Zdroj: | BMC Neurology BMC Neurology, Vol 19, Iss 1, Pp 1-6 (2019) |
| ISSN: | 1471-2377 |
| DOI: | 10.1186/s12883-019-1332-4 |
| Popis: | Background Type 2 Diabetes in Mexico has a high prevalence, 16–87% of patients may experience peripheral neuropathy. Early detection can prevent or halt its progression. The performance of Sudoscan in detecting neuropathy was compared to the Michigan Neuropathy Screening Instrument (MNSI). The aim was to identificate small fibers neuropathy. Methods Patients type 2 diabetes received both MNSI and sudomotor function assessment through measurement of electrochemical skin conductance (ESC) in the hands and feet. Results Two hundred twenty-one patients with neuropathy according to MNSI B had lower hands and feet ESC, regardless of diabetes duration. Among the 170 patients who had had diabetes for at least 5 years, 76 of them with normal MNSI B had abnormal hands or feet ESC; this was also the case in 28 out of 51 patients with diabetes than 5 or more years. In contrast, only 5 patients in the first group and 1 in the second group had abnormal MNSI B with normal ESC. Using MNSI B as a reference, abnormal hands or feet ESC ( |
| Databáze: | OpenAIRE |
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