Precision cancer medicine: What has translated into clinical use in Belgium?
| Autor: | M. Delnord, Aline Hebrant, Wannes Van Hoof, Anouk Waeytens, Els Van Valckenborgh, M Van den Bulcke, Aline Antoniou |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
0301 basic medicine
Cancer Research Medical education business.industry High-Throughput Nucleotide Sequencing Benchmarking Medical Oncology Data sharing 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Belgium Neoplasms 030220 oncology & carcinogenesis Knowledge translation Health care Humans Business Personalized medicine Precision Medicine Knowledge transfer Health policy Reimbursement |
| Zdroj: | Seminars in Cancer Biology. 84:255-262 |
| ISSN: | 1044-579X |
| Popis: | Rationale In 2016, Belgium launched the Next Generation Sequencing (NGS) Roadbook, consisting in 10 Actions, across the health care system, to facilitate the uptake of NGS in routine clinical practice. We compiled feedback on deployment of the NGS Roadbook from governmental stakeholders and beneficiaries: health policy makers, insurance providers, pathologists, geneticists, and oncologists. Main findings The Roadbook ensured the establishment of a Commission on Personalized Medicine and NGS testing guidelines. A national benchmarking trial ensued, and 10 networks of hospitals and laboratories adopted a reimbursement convention with the Belgian Health Insurance Agency. The Healthdata.be platform centralizes the collection of NGS metrics, and citizens were consulted on their views about NGS and genomics. Conclusion The Roadbook facilitated the implementation of NGS in routine (hemato-)oncology care in Belgium. Some challenges remain linked to data sharing and access by a wider range of stakeholders. Next steps include continuous monitoring of health outcomes and the budgetary impact. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect