| Autor: |
Ann M. Alex, Claudia Buss, Elysia Poggi Davis, Gustavo de los Campos, Kirsten A. Donald, Damien A. Fair, Nadine Gaab, Wei Gao, John H. Gilmore, Jessica B. Girault, Karen Grewen, Nynke A. Groenewold, Benjamin L. Hankin, Jonathan Ipser, Shreya Kapoor, Pilyoung Kim, Weili Lin, Shan Luo, Elizabeth S. Norton, Thomas G. O’Connor, Joseph Piven, Anqi Qiu, Jerod M. Rasmussen, Michael A. Skeide, Dan J. Stein, Martin A. Styner, Paul M. Thompson, Laurie Wakschlag, Rebecca Knickmeyer |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Biological Psychiatry |
| Popis: |
Imaging genetics provides an opportunity to discern associations between genetic variants and brain imaging phenotypes. Historically, the field has focused on adults and adolescents; very few imaging genetics studies have focused on brain development in infancy and early childhood (from birth to age six). This is an important knowledge gap as developmental changes in brain during the prenatal and early postnatal period are regulated by dynamic gene expression patterns that likely play an important role in establishing an individual’s risk for later psychiatric illness and neurodevelopmental disabilities. In this review, we summarize findings from imaging genetics studies spanning from early infancy to early childhood with a focus on studies examining genetic risk for neuropsychiatric disorders. We also introduce the Organization for Imaging Genomics in Infancy (ORIGINs), a working group of the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) consortium, which was established to facilitate large-scale imaging-genetics studies in infancy and early childhood. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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