A laboratory-based study of COVID-19 in Casablanca, Morocco
| Autor: | Nida Meskaouni, Jalila Rahoui, Chakib Nejjari, Imane Smyej, Jalila El Bakkouri, Hind Rida, Khadija Arouro, Idrissa Diawara, Hajar Elguazzar, Rachid Benmessaoud, Houda Benrahma, Fadoua Ousti, Salma Nahir, Khadija Jaras, Zineb Aouzal, Zahra Aadam, Fatima-Zahra Moujid, Leila Jeddan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Patient risk RT-PCR Reference laboratory Asymptomatic Risk zone Article 03 medical and health sciences 0302 clinical medicine Internal medicine Epidemiology medicine risk factors 030212 general & internal medicine 030304 developmental biology 0303 health sciences business.industry SARS-CoV-2 lcsh:Public aspects of medicine Public Health Environmental and Occupational Health COVID-19 lcsh:RA1-1270 University hospital laboratory test medicine.symptom business COVID-19 SARS-CoV-2 Risk factors Laboratory test RT-PCR |
| Zdroj: | Journal of Public Health in Africa Journal of Public Health in Africa (2020) |
| ISSN: | 2038-9922 |
| Popis: | Background: Given the spread of coronavirus disease 2019 (COVID-19) and its impact on human health, laboratory confirmation of diagnosis is essential. Objective: This study examined the contribution of laboratory diagnosis to the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the diagnosis of COVID- 19, taking into account patient risk of exposure to SARS-CoV-2, clinical symptoms and comorbidities. Methods: A cross-sectional, laboratory-based study was carried out from 1 April 2020 to 30 April 2020 at the National Reference Laboratory in Morocco using nasopharyngeal samples from patients admitted to the Cheikh Khalifa International University Hospital or other hospitals in Casablanca. A one-step reverse transcription real-time polymerase chain reaction (RT-PCR) was used to detect the presence of the SARS-CoV-2 genome. A national epidemiological investigation form was used to analyze patient exposure risk, clinical symptoms and comorbidities. Results: A total of 793 samples from 375 patients were analyzed and 1150 RT-PCR tests were conducted; 116 patients (30.93%) were COVID-19 positive. Travel to a risk zone, contact with a confirmed COVID-19 case and contact with a person who had been in a risk zone were significantly associated with being positive for COVID-19. Fever and cough were the main symptoms; 7.76 % of positive patients were asymptomatic. Conclusion: This is the first laboratory-based study in Morocco for the diagnosis of COVID- 19. Laboratory diagnosis of COVID-19 by RT-PCR associated with knowledge of exposure risk factors and clinical symptoms and comorbidities remains essential for clinicians for early, appropriate medical management COVID-19 patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|