Role of peripheral vestibular receptors in the control of blood pressure following hypotension
| Autor: | Min Sun Kim, Xiang-Lan Li, Byung Rim Park, Guang-Shi Jin, Yuan-Zhe Jin |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Epinephrine Physiology Review Article Dizziness Vestibulosympathetic reflex 03 medical and health sciences 0302 clinical medicine Vestibular nuclei medicine otorhinolaryngologic diseases Inner ear Vestibular Hair Cell Pharmacology Vestibular system business.industry Blood flow Peripheral 030104 developmental biology Blood pressure medicine.anatomical_structure Anesthesia Reflex sense organs Glutamate Hypotension business 030217 neurology & neurosurgery |
| Zdroj: | The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology |
| ISSN: | 1226-4512 |
| Popis: | Hypotension is one of the potential causes of dizziness. In this review, we summarize the studies published in recent years about the electrophysiological and pharmacological mechanisms of hypotension-induced dizziness and the role of the vestibular system in the control of blood pressure in response to hypotension. It is postulated that ischemic excitation of the peripheral vestibular hair cells as a result of a reduction in blood flow to the inner ear following hypotension leads to excitation of the central vestibular nuclei, which in turn may produce dizziness after hypotension. In addition, excitation of the vestibular nuclei following hypotension elicits the vestibulosympathetic reflex, and the reflex then regulates blood pressure by a dual-control (neurogenic and humoral control) mechanism. In fact, recent studies have shown that peripheral vestibular receptors play a role in the control of blood pressure through neural reflex pathways. This review illustrates the dual-control mechanism of peripheral vestibular receptors in the regulation of blood pressure following hypotension. |
| Databáze: | OpenAIRE |
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