A Strategy to Fight against Triple-Negative Breast Cancer: pH-Responsive Hexahistidine-Metal Assemblies with High-Payload Drugs
Autor: | Hongyan Xu, Xingjie Zan, Wenjuan Huang, Pengyan Hao, Xiaoxiao Wu, Long Zhang, Tinghong Zhang, Bo Peng |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | ACS applied bio materials. 3(8) |
ISSN: | 2576-6422 |
Popis: | Triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer, is difficult to be targeted therapeutically due to negative expression of the bioreceptor, which leads to the poorest overall four-year survival rate among all cancer subtypes. We proposed that the nanomedicine featuring high payload and pH-responsive release of the loaded drugs could assist the TNBC treatment. In the present study, the His |
Databáze: | OpenAIRE |
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