A Strategy to Fight against Triple-Negative Breast Cancer: pH-Responsive Hexahistidine-Metal Assemblies with High-Payload Drugs

Autor:	Hongyan Xu, Xingjie Zan, Wenjuan Huang, Pengyan Hao, Xiaoxiao Wu, Long Zhang, Tinghong Zhang, Bo Peng
Rok vydání:	2022
Předmět:	business.industry Biochemistry (medical) Biomedical Engineering General Chemistry medicine.disease Biomaterials Breast cancer Cancer research medicine Breast cancer cells skin and connective tissue diseases business Triple negative Triple-negative breast cancer
Zdroj:	ACS applied bio materials. 3(8)
ISSN:	2576-6422
Popis:	Triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer, is difficult to be targeted therapeutically due to negative expression of the bioreceptor, which leads to the poorest overall four-year survival rate among all cancer subtypes. We proposed that the nanomedicine featuring high payload and pH-responsive release of the loaded drugs could assist the TNBC treatment. In the present study, the His
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a238b50dff2e3d2631384793aa22dd01 https://pubmed.ncbi.nlm.nih.gov/35021707 Zobrazit plný text záznamu