Disentangling a complex nationwide Salmonella Dublin outbreak associated with raw-milk cheese consumption, France, 2015 to 2016
| Autor: | Amrish Baidjoe, Marie-Pierre Donguy, Nathalie Jourdan-Da Silva, Kostas Danis, Sabrina Cadel-Six, Dieter Van Cauteren, Laetitia Fabre, Aymeric Ung, Sophie Lefèvre, Caroline Guerrisi, Marie-Léone Vignaud, Louise Rossignol, Etienne Lucas, Simon Le Hello, Nizar Fawal, Renaud Lailler, Anne Morand |
|---|---|
| Přispěvatelé: | Santé publique France - French National Public Health Agency [Saint-Maurice, France], European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Centre National de Référence - National Reference Center Escherichia coli, Shigella et Salmonella (CNR-ESS), Institut Pasteur [Paris], European Programme for Public Health Microbiology Training (EUPHEM), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Sorbonne Université - Faculté de Médecine (SU FM), Sorbonne Université (SU), Direction Générale de l'Alimentation (DGAL), Ministère de l'agriculture, de l'agroalimentaire et de la forêt, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Université Paris-Est (UPE), European Centre for Disease Prevention and Control [Stockholm, Sweden] (ECDC), Institut Pasteur [Paris] (IP) |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Serotype Salmonella Epidemiology 030106 microbiology Prevalence Multiple Loci VNTR Analysis medicine.disease_cause cheese 03 medical and health sciences [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Virology Environmental health medicine raw-milk 2. Zero hunger business.industry Public Health Environmental and Occupational Health Outbreak Raw milk Food safety Salmonella Dublin 3. Good health 030104 developmental biology Geography outbreaks [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie France business WGS Food contaminant |
| Zdroj: | Eurosurveillance Eurosurveillance, European Centre for Disease Prevention and Control, 2019, 24 (3), ⟨10.2807/1560-7917.es.2019.24.3.1700703⟩ Eurosurveillance, 2019, 24 (3), ⟨10.2807/1560-7917.es.2019.24.3.1700703⟩ |
| ISSN: | 1560-7917 1025-496X |
| Popis: | On 18 January 2016, the French National Reference Centre for Salmonella reported to Santé publique France an excess of Salmonella enterica serotype Dublin (S. Dublin) infections. We investigated to identify the source of infection and implement control measures. Whole genome sequencing (WGS) and multilocus variable-number tandem repeat analysis (MLVA) were performed to identify microbiological clusters and links among cases, animal and food sources. Clusters were defined as isolates with less than 15 single nucleotide polymorphisms determined by WGS and/or with identical MLVA pattern. We compared different clusters of cases with other cases (case–case study) and controls recruited from a web-based cohort (case–control study) in terms of food consumption. We interviewed 63/83 (76%) cases; 2,914 controls completed a questionnaire. Both studies’ findings indicated that successive S. Dublin outbreaks from different sources had occurred between November 2015 and March 2016. In the case–control study, cases of distinct WGS clusters were more likely to have consumed Morbier (adjusted odds ratio (aOR): 14; 95% confidence interval (CI): 4.8–42) or Vacherin Mont d’Or (aOR: 27; 95% CI: 6.8–105), two bovine raw-milk cheeses. Based on these results, the Ministry of Agriculture launched a reinforced control plan for processing plants of raw-milk cheeses in the production region, to prevent future outbreaks. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|