The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale

Autor: Mark Tannenbaum, Teresa Coulson, Timothy D. Smith, Timothy D. Henry, Scott Sharkey, Christian W. Schmidt, Jenny Chambers, Santiago Garcia, Heather S. Rohm, Daniel Shivapour, Mehmet Yildiz, Frank V. Aguirre, Roberto Pacheco-Coronado, Ross Garberich
Rok vydání: 2020
Předmět:
CCL
Cardiac catheterization laboratory
medicine.medical_treatment
cardiac arrest
030204 cardiovascular system & hematology
registry
Ventricular Function
Left
0302 clinical medicine
CA
Cardiac arrest
ED
Emergency department
Risk Factors
030212 general & internal medicine
Myocardial infarction
PCI
Percutaneous coronary intervention
Registries
MHIF
Minneapolis Heart Institute Foundation
Stroke
LBBB
Left-bundle-branch block
AHA
American Heart Association
Cardiogenic shock
cardiogenic shock
angioplasty
General Medicine
D2B
Door-to-balloon
EMS
Emergency medical service
surgical procedures
operative
STEMI
ST-elevation myocardial infarction
myocardial infarction
Treatment Outcome
ECMO
Extracorporeal membrane oxygenation
CABG
Coronary artery bypass grafting
Female
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
PHI
Prairie Heart Institute
Shock
Cardiogenic
IHC
Iowa Heart Center
Culprit
National Death Index
Article
03 medical and health sciences
Percutaneous Coronary Intervention
Angioplasty
medicine
Humans
cardiovascular diseases
IABP
Intra-aortic balloon pump
business.industry
CS
Cardiogenic shock
EKG
Electrocardiogram
Infant
Newborn
Percutaneous coronary intervention
Stroke Volume
medicine.disease
TCH
The Christ Hospital
Emergency medicine
Conventional PCI
ST Elevation Myocardial Infarction
ACC
American College of Cardiology
business
Zdroj: Cardiovascular Revascularization Medicine
ISSN: 1878-0938
Popis: Background Over the past 20 years, the development of regional ST-elevation myocardial infarction (STEMI) care systems has led to remarkable progress in achieving timely coronary reperfusion with attendant improvement in clinical outcomes, including survival. Despite this progress, contemporary STEMI care does not consistently meet the national guideline-recommended goals, which offers an opportunity for further improvement in STEMI outcomes. The lack of single, comprehensive, national STEMI registry complicates our ability to improve STEMI outcomes in particular for high-risk STEMI subsets such as cardiac arrest (CA) and/or cardiogenic shock (CS). Objectives To address this need, the Midwest STEMI Consortium (MSC) was created as a collaboration of 4 large, regional STEMI care systems to provide a comprehensive, multicenter, and prospective STEMI registry without any exclusionary criteria. Methods The MSC is a collaboration of 4 large, regional STEMI care systems: Iowa Heart Center in Des Moines, IA; Minneapolis Heart Institute Foundation in Minneapolis, MN; Prairie Heart Institute in Springfield, IL; and The Christ Hospital in Cincinnati, OH. Each has similar standardized STEMI protocol and together include 6 percutaneous coronary intervention (PCI)-capable hospitals and over 100 non-PCI-capable hospitals. Each center had a prospective database that was transferred to a data coordinating center to create the multicenter database. The comprehensive database includes traditional risk factors, cardiovascular history, medications, time to treatment data, detailed angiographic characteristics, and short- and long-term clinical outcomes up to 5-year for myocardial infarction, stroke, and cardiovascular and all-cause mortality. Ten-year mortality rates were assessed by using national death index. Results Currently, the comprehensive database (03/2003-01/2020) includes 14,911 consecutive STEMI patients with mean age of 62.3 ± 13.6 years, female gender (29%), and left anterior descending artery as the culprit vessel (34%). High risk features included: Age >75 years (19%), left ventricular ejection fraction
Highlights • There is no single, comprehensive, and national STEMI registry. In particular, detailed information regarding high-risk STEMI patients including cardiac arrest (CA) and cardiogenic shock (CS) are frequently missing. • Midwest STEMI Consortium is a unique registry of over 15,000 consecutive patients from 4 large regional STEMI systems. • Unique aspects of the registry include: • Consecutive STEMI activations without exclusions. • Detailed data on high-risk (CA/CS) cohorts. • Detailed angiographic data. • Detailed long-term follow up including mortality to 10 years.
Databáze: OpenAIRE
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