The effect of Δ7-cholestenol feeding on the cholesterol and lipoproteins of rabbit serum
| Autor: | Frank T. Pierce, Max W. Biggs, Richard M. Lemmon, David Kritchevsky, Margaret A. Parsons |
|---|---|
| Rok vydání: | 1954 |
| Předmět: |
medicine.medical_specialty
Cholesterol Lipoproteins Biophysics Biology Biochemistry Sterol chemistry.chemical_compound Blood Blood serum Qualitative analysis Endocrinology Blood chemistry chemistry Internal medicine medicine Animals lipids (amino acids peptides and proteins) Rabbits Molecular Biology Serum cholesterol Lipoprotein |
| Zdroj: | Archives of Biochemistry and Biophysics. 51:161-169 |
| ISSN: | 0003-9861 |
| DOI: | 10.1016/0003-9861(54)90464-6 |
| Popis: | 1. 1.When Δ 7 -cholestenol is fed to rabbits there is produced a rise in the various classes of low-density serum lipoproteins. The lipoprotein “pattern” is qualitatively the same as that observed after feeding cholesterol. 2. 2. Δ 7 -Cholestenol produces a striking rise in serum cholesterol, and about the same levels are reached as are observed on feeding cholesterol itself. The sterols of the serum after this feeding show a maximum of about 12% of Δ 7 -cholestenol. 3. 3. Δ 7 -Cholestenol and cholesterol produce an additive effect on the levels of serum lipoproteins when fed simultaneously. 4. 4. Five per cent of the serum sterols is Δ 7 -cholestenol at the end of 1 week of feeding both this sterol and cholesterol. At the end of 2 weeks the Δ 7 -cholestenol falls almost to zero in spite of continued feeding of both sterols. |
| Databáze: | OpenAIRE |
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