Analyse der Knochendeformation und Muskelkräfte der menschlichen Tibia

Autor: Kriechbaumer, Andreas
Přispěvatelé: Itskov, Mikhail, Rittweger, Jörn
Jazyk: němčina
Rok vydání: 2019
Předmět:
Zdroj: Aachen : RWTH Aachen University, Lehr-und Forschungsgebiet Kontinuumsmechanik, Bericht / RWTH Aachen University, Lehr-und Forschungsgebiet Kontinuumsmechanik 10, 1 Online-Ressource (XI, 142 Seiten) : Illustrationen, Diagramme (2019). doi:10.18154/RWTH-2020-00369 = Dissertation, RWTH Aachen University, 2019
DOI: 10.18154/RWTH-2020-00369
Popis: Dissertation, RWTH Aachen University, 2019; Aachen : RWTH Aachen University, Lehr- und Forschungsgebiet Kontinuumsmechanik, Bericht / RWTH Aachen University, Lehr- und Forschungsgebiet Kontinuumsmechanik 10, 1 Online-Ressource (XI, 142 Seiten) : Illustrationen, Diagramme (2019). = Dissertation, RWTH Aachen University, 2019
A basic understanding of the adaptation of bone is essential for the exploration of space by humans, but also for human health on earth in general. The regulation of bone growth and decrease is controlled by its deformation, which in turn results from the mechanical loading of the bone. Understanding these connections, knowing the effects of different activities on the deformation of the bone, and being able to put them into relation, is the key to the fundamental understanding sought. In the course of this thesis, a method was developed to establish these relationships qualitatively and quantitatively. Based on in vivo measurements on the tibia, an algorithm was developed for the in silico analysis of the available data. The latter makes use of the implications of Hooke's law in the form of the superposition principle, in order to quasi-inverse determine the forces necessary to achieve the measured deformation. These can be used in a Finite Element Analysis (FEA) with the reconstructed tibia bones to determine their stress-strain state. For validation of the assumptions and boundary conditions of the algorithm a biomechanical test rig was constructed. With it, examinations were carried out in replica and ex vivo. For this purpose, tibia replicas of composite material or respectively cadaverous legs were artificially impacted by actuators, and the deformation movement of the bone was measured via a special application of motion capturing. The analysis of the in vivo data by means of the in silico analysis provided quantitative results on the average values and peak values of strain in the tibia, and this for various everyday activities. These results, however, are not limited to a single measuring point, as opposed to the current standard method, but cover the complete reconstructed area of the tibia. This led to the conclusion that the currently assumed peak values are listed too low. In addition, the analysis shows a temporal and local variance of the peak strain in the bone over the course of an activity. These results alter the previous understanding of bone adaptation and its regulatory mechanisms.
Published by RWTH Aachen University, Lehr- und Forschungsgebiet Kontinuumsmechanik, Aachen
Databáze: OpenAIRE