Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends
| Autor: | Joseph R. Kallini, Amor Khachemoune, Nouran S. Hamed |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Skin Neoplasms medicine.diagnostic_test business.industry medicine.medical_treatment Photodynamic therapy Dermatology Prognosis medicine.disease Cryosurgery Curettage Radiation therapy Epidemiology Biopsy Carcinoma Squamous Cell medicine Carcinoma Humans Skin cancer business |
| Zdroj: | International Journal of Dermatology. 54:130-140 |
| ISSN: | 0011-9059 |
| Popis: | Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer. It originates from epidermal keratinocytes or adnexal structures (such as eccrine glands or pilosebaceous units). We describe the salient features of cutaneous SCC. We also review novel classification schemes proposed during the last decade which attempt to stratify SCC lesions based on prognosis. Biopsy leads to definitive diagnosis. Treatment includes surgical excision; Mohs micrographic surgery produces excellent cure rates and spares the maximal amount of tissue. Other modalities include electrodessication and curettage, cryosurgery, radiotherapy, topical medications, photodynamic therapy, and systemic therapy. Management and follow-up depend on the risk stratification of individual lesions. |
| Databáze: | OpenAIRE |
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