Enantioselective synthesis of aryl sulfoxides via palladium-catalyzed arylation of sulfenate anions

Autor:	David Madec, Guillaume Prestat, Guillaume Maitro, Sophie Vogel, Giovanni Poli, Mounel Sadaoui
Rok vydání:	2007
Předmět:	Ligand Aryl Organic Chemistry Enantioselective synthesis chemistry.chemical_element Biochemistry Medicinal chemistry Catalysis chemistry.chemical_compound Enantiopure drug chemistry Organic chemistry Physical and Theoretical Chemistry Palladium
Zdroj:	Organic letters. 9(26)
ISSN:	1523-7060
Popis:	Arylation of various sulfenate anions generated from beta-sulfinyl esters by retro-Michael reaction in the presence of palladium(0) and enantiopure ligands gave the corresponding aryl sulfoxides in enantio-enriched form. The Josiphos-type ligand (R)-(S)-PPF-t-Bu2 turned out to be the best ligand tested, allowing ee's up to 83% in a predictable sense.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ff97ed24c7e7996e1e5ec72b5d20f6 https://pubmed.ncbi.nlm.nih.gov/18034497 Zobrazit plný text záznamu