Characterization of Gazdar murine sarcoma virus by nucleic acid hybridization and analysis of viral expression in cells
| Autor: | D K Haapala, L A Phillips, R H Pang |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
endocrine system
viruses Immunology Hamster Viral transformation Biology Microbiology Genome Virus Homology (biology) Cell Line Sarcoma Viruses Murine Viral Proteins Nucleic acid thermodynamics Virology medicine neoplasms Base Sequence Nucleic Acid Hybridization medicine.disease Molecular biology Leukemia Insect Science Nucleic acid RNA Viral Gammaretrovirus Moloney murine leukemia virus Research Article |
| Zdroj: | Journal of Virology. 24:551-556 |
| ISSN: | 1098-5514 0022-538X |
| Popis: | Gazdar murine sarcoma virus (Gz-MSV) and Moloney murine sarcoma virus (M-MSV) are closely related. The complete M-MSV-specific nucleic acid sequences constituted a major portion of Gz-MSV-specific sequences. The MSV-specific sequences in both Gz-MSV and M-MSV genomes shared homology with hamster leukemia virus nucleic acid sequences. Both rat cells (S+L+) and hamster (S+L-) cells expressed two viral proteins of 68,000 and 70,000 daltons. These proteins were immunologically related to p60 purified from m1 virions of M-MSV. |
| Databáze: | OpenAIRE |
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