Characteristics of ovarian follicular development in Norplant users
| Autor: | Janet Horenstein, Maria Lacarra, Donna Shoupe, Daniel R. Mishell, Arnold L. Medearis |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Population Library science Levonorgestrel Luteal phase Menstruation Follicle-stimulating hormone Ovarian Follicle Reference Values Follicular phase Contraceptive Agents Female Humans Medicine education Ovulation Progesterone Menstrual cycle media_common Gynecology education.field_of_study business.industry Norgestrel Osmolar Concentration Obstetrics and Gynecology General Medicine Luteinizing Hormone Reproductive Medicine Work (electrical) Female Follicle Stimulating Hormone Contraceptive implant business Blood sampling |
| Zdroj: | Fertility and Sterility. 55:766-770 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(16)54245-9 |
| Popis: | Daily transvaginal ultrasound (US) scanning of the ovaries to assess follicular development and daily blood sampling were performed on 19 Norplant (Leiras, Turku, Finland) subdermal contraceptive implant users who had regular menstrual cycles and on 10 normally cycling women. Three groups were identified in the implant users based on US finding. Six (31.6%) of the implant users had US findings that were consistent with a normal ovulatory pattern. However, their mean peak luteinizing hormone levels and peak midluteal phase progesterone (P) levels were significantly lower than control values. Eleven (57.9%) users had persistent follicles, and 2 users (10.5%) had no follicular development. These data suggest that after 2 to 4 years of use, about one third of Norplant users with regular bleeding patterns may ovulate but most have deficient luteal P levels. In this small study, the presence of persistent follicular enlargement in implant users was common. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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