Evaluation of a novel method for measuring tissue blood flow and gases
| Autor: | S. Aagaard, Lars Riis Damgaard, John Michael Hasenkam, Jette Scheby Berg |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
tissue flow
Transducers Ischemia Mass Spectrometry Hemoglobins TOURNIQUET myocardium medicine ischaemia and reperfusion Animals Fiber Optic Technology skeletal muscle Muscle Skeletal Chemistry Myocardium Mechanical Engineering diffusion Equipment Design Prostheses and Implants General Medicine Blood flow tissue vitality Hypoxia (medical) medicine.disease Coronary Vessels ISCHEMIA Equipment Failure Analysis Oxygen Clinical Practice Reperfusion Injury wash out SKELETAL-MUSCLE Blood supply medicine.symptom Rheology Blood Flow Velocity inert gases Biomedical engineering |
| Zdroj: | Aagaard, N K, Damgaard, LR, Berg, JS & Hasenkam, JM 2005, ' Evaluation of a novel method for measuring tissue blood flow and gases ', Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, vol. 219, no. H1, pp. 71-75 . https://doi.org/10.1243/095441105X9255 |
| ISSN: | 2041-3033 0954-4119 |
| DOI: | 10.1243/095441105x9255 |
| Popis: | In clinical practice a method for assessment of tissue vitality is a sought - after tool. We have developed a new sensor principle, which is able to register changes in tissue concentration of O2 and tissue flow. The technique is based on diffusion of inert gases and mass spectrometer detection of gaseous metabolites. It was hypothesized that the new sensor could register changes in vital parameters after induction and release of an ischaemic insult to muscular tissue. The sensor performance was evaluated in ten anaesthetized pigs subjected to local muscular ischaemia. Preliminary data from this study indicate the validity of registered hypoxia and reduction in tissue flow as a consequence of compromised blood supply. It was concluded that although precise calibration of the technique is not yet established, it holds promise as a technique that can be used to monitor changes in tissue vitality. |
| Databáze: | OpenAIRE |
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