Pentafluorobenzylation of the fungicide metabolite fenpropimorphic acid for GC/MS investigations of soil samples

Autor:	M. Bahadir, H. Dieckmann, Robert Kreuzig
Rok vydání:	1996
Předmět:	Detection limit chemistry.chemical_compound Chemical ionization Chromatography Chemistry Diazomethane Metabolite Gas chromatography Gas chromatography–mass spectrometry Derivatization Mass spectrometry Biochemistry Analytical Chemistry
Zdroj:	Analytical and Bioanalytical Chemistry. 355:183-186
ISSN:	1618-2650 1618-2642
DOI:	10.1007/s0021663550183
Popis:	For the determination of fenpropimorphic acid in soil samples, a derivatization step with pentafluorobenzylbromide has been established in order to perform GC/MS with negative chemical ionization. In spite of forming the electrophilic pentafluorobenzyl ester, only the fenpropimophic acid anion was detected. Additional derivatization reactions with diazomethane and 2,2,2-trichloroethanol showed that the formation of this acid anion was depending on the leaving group. In comparison with the determination of the methyl ester with GC/MS and electron impact ionization, the detection limit was however improved from 10 microg/kg to 2 microg/kg dry soil and the analytical quality was ensured due to higher stability of the pentafluorobenzyl ester standards.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eb4dfebfcc9ee17155676c84804be7 https://doi.org/10.1007/s0021663550183 Zobrazit plný text záznamu Full text from SpringerLink