Impaired right and left ventricular mechanics in adults with pulmonary hypertension and congenital shunts
| Autor: | Maria Jose Rodriguez-Puras, Rocío Toro, Maria Luisa Cabeza-Letrán, Alipio Mangas, Maribel Quezada |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Hypertension Pulmonary Diastole 030204 cardiovascular system & hematology Doppler imaging Ventricular Function Left 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine medicine.artery Medicine Humans 030212 general & internal medicine Prospective Studies Prospective cohort study Ejection fraction business.industry General Medicine Eisenmenger Complex Middle Aged medicine.disease Pulmonary hypertension medicine.anatomical_structure Ventricle Echocardiography Eisenmenger syndrome Case-Control Studies Pulmonary artery Cardiology Ventricular Function Right Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of cardiovascular medicine (Hagerstown, Md.). 17(3) |
| ISSN: | 1558-2035 |
| Popis: | AIMS To assess left ventricle mechanics in Eisenmenger physiology patients with congenital shunts, and their relationship with the right ventricle, and to consider the clinical usefulness of this information. METHODS The study involved 28 patients with pulmonary artery hypertension (PAH) and congenital shunt, matched with 28 healthy participants. Standard echocardiography and pulsed wave tissue Doppler imaging were employed to analyze systolic and diastolic ventricular function, the myocardial performance index (MPI) of ventricles, and the strain and strain rate along the left ventricle lateral wall, septum, and right ventricle free wall. RESULTS The left ventricle ejection fraction was similar in the two groups. However, despite normal standard left ventricle measures, patients presented parameters of defective myocardial mechanics: mitral peak systolic velocity (S') (cm/s) (8.6 (7.6-10.9) vs. 10.7 (8.6-12.5); P = 0.002) was higher, whereas left ventricle-MPI was lower (0.54 ± 01 vs. 0.32 ± 0.07, P |
| Databáze: | OpenAIRE |
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