Feasibility of large-scale population testing for SARS-CoV-2 detection by self-testing at home
| Autor: | Javier Crespo, Lorena Cayon, Ana Álvarez-Cancelo, Víctor M. Martínez-Taboada, Emilio Fábrega, Tatiana Fernández-Lanas, Alvaro Santos-Laso, Paula Iruzubieta, Reinhard Wallmann, Jeffrey V. Lazarus, Joaquín Cabezas, Soraya Curiel-Olmo, Laura Rasines, Marcos López-Hoyos, José L. Hernández, Agustín García-Blanco |
|---|---|
| Přispěvatelé: | Universidad de Cantabria |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Adolescent Cross-sectional study Science Population Diseases Article Cohort Studies 03 medical and health sciences Young Adult 0302 clinical medicine Health care medicine Seroprevalence Humans 030212 general & internal medicine Young adult education Aged education.field_of_study Multidisciplinary business.industry SARS-CoV-2 COVID-19 Middle Aged Test (assessment) 030104 developmental biology Cross-Sectional Studies Self-Testing Spain Scale (social sciences) Immunoglobulin G Emergency medicine Feasibility Studies Medicine Female business Cohort study |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) Scientific Reports Sci Rep . 2021 May 10;11(1):9819 UCrea Repositorio Abierto de la Universidad de Cantabria Universidad de Cantabria (UC) |
| ISSN: | 2045-2322 |
| Popis: | The simplicity and low cost of rapid point-of-care tests greatly facilitate large-scale population testing, which can contribute to controlling the spread of the COVID-19 virus. We evaluated the applicability of a self-testing strategy for SARS-CoV2 in a population-based, cross-sectional study in Cantabria, Spain, between April and May 2020. For the self-testing strategy, participants received the necessary material for the self-collection of blood and performance of a rapid antibody test using lateral flow immunoassay at home without the supervision of healthcare personnel. A total of 1,022 participants were enrolled. Most participants correctly performed the COVID-19 self-test the first time (91.3% [95% CI 89.4-92.9]). Only a minority of the participants (0.7%) needed the help of healthcare personnel, while 6.9% required a second kit delivery, for a total valid test result in 96.9% of the participants. Incorrect use of the self-test was not associated with the educational level, age over 65, or housing area. Prevalence of IgG antibodies against SARS-CoV2 for subjects with a valid rapid test result was 3.1% (95% CI 2.2-4.4), similar to the seroprevalence result obtained using a conventional approach carried out by healthcare professionals. In conclusion, COVID-19 self-testing should be considered as a screening tool. Acknowledgements: We would like to acknowledge the participation of all the individuals in this study. JVL acknowledges support to ISGlobal from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Programme (CEX2018-000806-S), and from the Government of Catalonia through the CERCA Programme. |
| Databáze: | OpenAIRE |
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