Synthesis of a sucrose-based macrocycle with unsymmetrical monosaccharides 'arms'
| Autor: | Mykhaylo A. Potopnyk, Sławomir Jarosz, Karolina Tiara |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Sucrose 010405 organic chemistry Stereochemistry Organic Chemistry sucrose ring-closing metathesis 010402 general chemistry Ring (chemistry) 01 natural sciences Full Research Paper 0104 chemical sciences lcsh:QD241-441 Chemistry chemistry.chemical_compound Ring-closing metathesis lcsh:Organic chemistry chemistry Yield (chemistry) Monosaccharide lcsh:Q chiral macrocycles lcsh:Science Derivative (chemistry) |
| Zdroj: | Beilstein Journal of Organic Chemistry Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 634-641 (2018) |
| ISSN: | 1860-5397 |
| DOI: | 10.3762/bjoc.14.50 |
| Popis: | An efficient methodology for the selective substitution of both terminal positions (C6 and C6’) in 1’,2,3,3’,4,4’-hexa-O-benzylsucrose with different unsaturated monosaccharide units is presented. Such a highly functionalized intermediate was cyclized under RCM conditions to afford a macrocyclic derivative containing a 31-membered ring in 26% yield. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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