Extracellular Ser/Thr/Tyr phosphorylated proteins of Pseudomonas aeruginosa PA14 strain
| Autor: | Thierry Jouenne, Tassadit Ouidir, Pascal Cosette, Frédérique Jarnier, Julie Hardouin |
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| Rok vydání: | 2014 |
| Předmět: |
inorganic chemicals
Molecular Sequence Data Virulence Biology medicine.disease_cause Biochemistry Mass Spectrometry Microbiology Serine Bacterial Proteins Extracellular medicine Protein phosphorylation Amino Acid Sequence Threonine Amino Acids Phosphorylation Molecular Biology Pseudomonas aeruginosa Membrane Proteins Phosphoproteins enzymes and coenzymes (carbohydrates) Signal transduction Extracellular Space |
| Zdroj: | Proteomics. 14(17-18) |
| ISSN: | 1615-9861 |
| Popis: | Protein phosphorylation on serine, threonine, and tyrosine is known to be involved in a wide variety of cellular processes, signal transduction, and bacterial virulence. We characterized, for the first time, the extracellular phosphoproteins of the Pseudomonas aeruginosa PA14 strain. We identified 28 phosphoproteins (59 phosphosites) including enzymes, with various phosphorylation sites, known as potent secreted virulence factors in P. aeruginosa. The high phosphorylation level of these virulence factors might reflect a relationship between Ser/Thr/Tyr phosphorylation and virulence. |
| Databáze: | OpenAIRE |
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