Herpes Simplex Virus Type 2 Acute Retinal Necrosis in an Immunocompetent Patient
Autor: | Rosario Brancato, C S Foster, Giulio Modorati, Claudio Azzolini, Elisabetta Miserocchi |
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Rok vydání: | 2003 |
Předmět: |
Male
medicine.medical_specialty Visual acuity genetic structures Anterior Chamber Fundus Oculi Herpesvirus 2 Human Prednisolone medicine.medical_treatment Eye disease Visual Acuity Eye Infections Viral Retinitis Vitrectomy Antiviral Agents Polymerase Chain Reaction 03 medical and health sciences 0302 clinical medicine Ophthalmology medicine Humans Ganciclovir Glucocorticoids business.industry Retinal Detachment Retinal detachment Herpes Simplex Retinal Necrosis Syndrome Acute General Medicine Middle Aged Eye infection medicine.disease eye diseases Surgery Vitreous Body Treatment Outcome DNA Viral 030221 ophthalmology & optometry sense organs Acute retinal necrosis Cytomegalovirus retinitis medicine.symptom business 030217 neurology & neurosurgery |
Zdroj: | European Journal of Ophthalmology. 13:99-102 |
ISSN: | 1724-6016 1120-6721 |
Popis: | Purpose To report a case of acute retinal necrosis caused by herpes simplex virus 2 in an otherwise healthy patient. Case report A 45-year-old man presented with one month's history of decreased vision in the right eye. He had previously received a course of intravenous gancyclovir because of a clinical suspicion of cytomegalovirus retinitis. The patient's ocular history was remarkable for a similar episode in the left eye thirty years earlier, resulting in important visual impairment. System and laboratory investigations were unremarkable. Ocular examination showed severe anterior granulomatous uveitis, vitreous haze, areas of necrosis and retinal exudates. The anterior chamber tap disclosed the presence of HSV type 2, and oral steroids and acyclovir were instituted. Two weeks after the patient had been discharged, a retinal detachment occurred in the right eye, necessitating surgical repair. The presence of HSV type 2 was confirmed in the vitreous. Visual acuity recovered completely after surgery and the patient was placed on a maintenance dose of oral acyclovir. Conclusions HSV type 2 is a rare cause of acute retinal necrosis in healthy patients. Bilateral involvement can occur in the fellow eye, even with a long delay. Acute retinal necrosis is a severe ocular inflammatory syndrome associated with a very poor visual outcome. It is caused by VZV, HSV type 1 and, less commonly, by HSV type 2. The disease can affect healthy patients and cause bilateral involvement in the fellow eye, even with a long delay. |
Databáze: | OpenAIRE |
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