Kinetics of Plasma Refilling During Hemodialysis Sessions with Different Initial Fluid Status
| Autor: | Mauro Pietribiasi, Joanna Stachowska-Pietka, Jacek Waniewski, Krassimir Katzarski, Bengt Lindholm, Daniel Schneditz, Magda Galach |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Oncotic pressure medicine.medical_treatment Kinetics Body water Biomedical Engineering Biophysics Ultrafiltration Bioengineering Blood volume Hemodiafiltration Biomaterials medicine Humans Aged Aged 80 and over Blood Volume Chemistry Plasma refilling General Medicine Middle Aged Ultrafiltration (renal) Volume (thermodynamics) Anesthesia Female Hemodialysis |
| Zdroj: | ASAIO Journal. 61:350-356 |
| ISSN: | 1058-2916 |
| DOI: | 10.1097/mat.0000000000000206 |
| Popis: | Removal of fluid excess from the plasma volume by ultrafiltration during hemodialysis (HD) is balanced by plasma refilling from the interstitium, driven mainly by the increase in plasma oncotic pressure. We calculated the plasma refilling coefficient (Kr, a parameter expressing the ratio of refilling rate to the increase in oncotic pressure) for nine patients, each undergoing two HD sessions differing by pretreatment fluid status and session time (shorter session, SH, 3.5 h, and longer session, LH, 4.5h). Relative blood volume change was measured online, and solute concentrations were measured regularly during the sessions. The volume of body compartments was measured by bioimpedance. The patients were more volume expanded before LH session (higher initial body mass and total body water). Oncotic pressure was similar for both sessions. The refilling rate, despite higher fluid overload in the LH sessions, was similar for both sessions. The final Kr values stabilized on similar levels (SH: 136.6 ± 55.6 ml/mm Hg/h and LH: 150.7 ± 73.6 ml/mm Hg/h) at similar times, notwithstanding the difference in initial fluid overload between the two groups, suggesting that Kr at dry weight is relatively insensitive to the initial fluid status of the patient. |
| Databáze: | OpenAIRE |
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