Comparison of NOGA Endocardial Mapping and Cardiac Magnetic Resonance Imaging for Determining Infarct Size and Infarct Transmurality for Intramyocardial Injection Therapy Using Experimental Data
| Autor: | Hendrik Jan Ankersmit, Mariann Gyöngyösi, Matthias Zimmermann, Maximilian Y. Emmert, Gerald Maurer, Georg Strebinger, Andras Jakab, Simon P. Hoerstrup, Petra Wolint, Noemi Pavo |
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| Přispěvatelé: | University of Zurich, Pavo, Noemi |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Swine Cardiology Myocardial Infarction Infarction lcsh:Medicine 610 Medicine & health Gadolinium 1100 General Agricultural and Biological Sciences Transmural infarction Imaging Three-Dimensional 1300 General Biochemistry Genetics and Molecular Biology Cardiac magnetic resonance imaging Internal medicine medicine Medicine and Health Sciences Animals Myocardial infarction Cardiovascular Imaging lcsh:Science Endocardium 1000 Multidisciplinary Multidisciplinary medicine.diagnostic_test business.industry lcsh:R Injection therapy Magnetic resonance imaging medicine.disease Infarct size Magnetic Resonance Imaging 10020 Clinic for Cardiac Surgery Disease Models Animal Cardiovascular Diseases Heart Function Tests cardiovascular system lcsh:Q business Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 11, p e113245 (2014) |
| ISSN: | 1932-6203 |
| Popis: | OBJECTIVES: We compared the accuracy of NOGA endocardial mapping for delineating transmural and non-transmural infarction to the results of cardiac magnetic resonance imaging (cMRI) with late gadolinium enhancement (LE) for guiding intramyocardial reparative substance delivery using data from experimental myocardial infarction studies. METHODS: Sixty domestic pigs underwent diagnostic NOGA endocardial mapping and cMRI-LE 60 days after induction of closed-chest reperfused myocardial infarction. The infarct size was determined by LE of cMRI and by delineation of the infarct core on the unipolar voltage polar map. The sizes of the transmural and non-transmural infarctions were calculated from the cMRI transmurality map using signal intensity (SI) cut-offs of>75% and>25% and from NOGA bipolar maps using bipolar voltage cut-off values of |
| Databáze: | OpenAIRE |
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