Advancing paternal age does not affect in-vitro fertilization (IVF) outcomes in a Saudi population
| Autor: | Faisel Yunus, Samaher Saud Alfaraj |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Infertility
medicine.medical_specialty lcsh:QH471-489 Reproductive endocrinology and infertility medicine.medical_treatment Population Anovulation Paternal age Human fertilization Obstetrics and Gynaecology medicine IVF outcomes lcsh:Reproduction education Maternal age Gynecology education.field_of_study lcsh:R5-920 In vitro fertilisation business.industry urogenital system Obstetrics and Gynecology medicine.disease Sperm Pregnancy rate Reproductive Medicine Semen parameters business lcsh:Medicine (General) |
| Zdroj: | Middle East Fertility Society Journal, Vol 20, Iss 3, Pp 204-208 (2015) |
| ISSN: | 1110-5690 |
| Popis: | Objective To evaluate the effect of paternal age on in-vitro fertilization (IVF) outcomes. Design Retrospective cohort study. Setting Reproductive Endocrinology and Infertility Unit. Patients The study included 451 couples undergoing their first IVF cycle. Main outcome measures Effect of advancing paternal age on: semen parameters; IVF cycle-related factors e.g., number of oocyte retrieved, fertilization rate, high quality embryo rate; and IVF outcome i.e., pregnancy rate. Results The mean paternal age in our study was 36.3 years (range: 24–76 years). Approximately half of the study couples (51.9%) had secondary infertility with anovulation being the major cause. We found no significant correlations between the advancing paternal age and the semen parameters – sperm volume ( p = 0.28), sperm concentration ( p = 0.47), or sperm motility ( p = 0.91). IVF cycle-related factors did not significantly differ for advancing paternal age groups – number of oocyte retrieved ( p = 0.52), number of embryos fertilized ( p = 0.14), fertilization rate ( p = 0.94), or the high quality embryo rate ( p = 0.84). Likewise, we found no significant association between the advancing paternal age and the positive IVF outcome i.e., the positive serum pregnancy test ( p = 0.64). Conclusion Advancing paternal age does not affect the IVF outcomes in a Saudi population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|