Effect of chitosan and Aloe Vera extract concentrations on the physicochemical properties of chitosan biofilms
| Autor: | Classius Ferreira da Silva, Patrícia Severino, Murilo Santos Pacheco, Cristiana Maria Pedroso Yoshida, Mariana Agostini de Moraes, Patricia Santos Lopes, Eliana B. Souto |
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| Přispěvatelé: | Universidade do Minho |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Polymers and Plastics
wound healing 02 engineering and technology 010402 general chemistry 01 natural sciences Fluid handling Aloe vera Article Chitosan lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry chitosan membrane moisture vapor transmission rate color parameters Science & Technology biology Chemistry Biofilm General Chemistry 021001 nanoscience & nanotechnology biology.organism_classification 0104 chemical sciences 3. Good health Chitosan membrane aloe vera tensile strength Wound dressing 0210 nano-technology Nuclear chemistry Moisture vapor transmission rate |
| Zdroj: | Polymers Volume 13 Issue 8 Polymers, Vol 13, Iss 1187, p 1187 (2021) Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| Popis: | Chitosan films have been extensively studied as dressings in formulations for the treatment of chronic wounds. The incorporation of aloe vera (Aloe barbadensis Miller) into chitosan dressings could potentialize the healing process since aloe vera shows several pharmacological activities. This work aimed to evaluate the effect of aloe vera and chitosan concentrations on the physicochemical properties of the developed films. The films were obtained by casting technique and characterized with respect to their color parameters, morphology, barrier and mechanical properties, and thermal analysis. Results showed that the presence of aloe vera modified the films color parameters, changed barrier properties, increased fluid handling capacity (FHC), and decreased water-vapor permeability (WVP). The reduced elongation at break resulted in more rigid films. Aloe vera concentration did not significantly change film properties, but the presence of this gel increased the films stability at temperatures below 200 °C, showing similar behavior as chitosan films above 400 °C. The results suggest a crosslinking/complexation between chitosan and aloe vera, which combine appropriate physicochemical properties for application as wound dressing materials. This work was supported by São Paulo Research Foundation (FAPESP) (2010/17.721-4), Portuguese Science and Technology Foundation (FCT) through the projects M-ERA-NET/0004/2015 (PAIRED) and UIDB/04469/2020 (strategic fund) funded by national funds, and co-financed Education (FCT/MEC) from national funds and FEDER, under the Partnership Agreement PT202 info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
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