Changing patterns of hepatitis A prevalence within the Saudi population over the last 18 years
| Autor: | Saleh Al Ansari, Faleh Z. Al Faleh, Yaqoub Al Mazrou, Suliman Al Shehri, Ahmad Shaffi, Ayman A. Abdo, Mohammed Al Jeffri |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent viruses Population Saudi Arabia MEDLINE Antibodies Viral Serology parasitic diseases Epidemiology Prevalence medicine Humans Longitudinal Studies skin and connective tissue diseases education education.field_of_study biology business.industry Gastroenterology virus diseases Hepatitis A General Medicine medicine.disease Virology digestive system diseases eye diseases Hepatitis a virus Social Class Immunoglobulin G biology.protein Female Hepatitis A virus sense organs Antibody business Rapid Communication geographic locations |
| Zdroj: | World Journal of Gastroenterology. 14:7371 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.14.7371 |
| Popis: | To determine the seroprevalence of Hepatitis A (HAV) amongst Saudi children and compare it with previously reported prevalence data from the same population.A total of 1357 students were randomly selected between the ages of 16 and 18 years (689 males and 668 females) from three different regions of Saudi Arabia (Madinah, Al-Qaseem, and Aseer) and tested for anti-HAV-IgG.The overall prevalence of anti-HAV-IgG among the study population was 18.6%. There was no difference between males and females but there was a significant difference in the seroprevalence (P = 0.0001) between the three different regions, with Madinah region showing the highest prevalence (27.4%). When classified according to socioeconomic status, lower class students had a prevalence of 36.6%, lower middle class 16.6%, upper middle class 9.6%, and upper class 5.9% (P = 0.0001). Comparing the current study results with those of previous studies in 1989 and 1997 involving the same population, there was a marked reduction in the overall prevalence of HAV from 52% in 1989, to 25% in 1997, to 18.6% in 2008 (P0.0001).Over the last 18 years, there has been a marked decline in the prevalence of HAV in Saudi children and adolescents. The current low prevalence rates call for strict adherence to vaccination policies in high-risk patients and raises the question of a universal HAV vaccination program. |
| Databáze: | OpenAIRE |
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