Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT)

Autor: Sophie Cassidy, Michael Trenell, Renae J. Stefanetti, Sarah J. Charman, Alison C. Barnes, Naomi Brosnahan, Louise McCombie, George Thom, Carl Peters, Sviatlana Zhyzhneuskaya, Wilma S. Leslie, Christopher Catt, Michael Catt, Alex McConnachie, Naveed Sattar, Falko F. Sniehotta, Michael E. J. Lean, Roy Taylor
Rok vydání: 2022
Předmět:
Zdroj: Diabetic medicine : a journal of the British Diabetic AssociationREFERENCES.
ISSN: 1464-5491
Popis: As sustained weight loss is vital for achieving remission of type 2 diabetes, we explored whether randomisation to weight loss plus maintenance in the DiRECT trial was associated with physical activity, inactivity or sleep.Participants were randomised to either a dietary weight management programme or best-practice care. The weight management group were encouraged to increase daily physical activity to their sustainable maximum. Objective measurement was achieved using a wrist-worn GENEActiv accelerometer for 7 days at baseline, 12 and 24 months in both groups.Despite average weight loss of 10 kg at 12 months in the intervention (n = 66) group, there were no differences in total physical activity or inactivity compared with the control (n = 104) at any time point. However, in our exploratory analysis, those who lost more than 10% of their baseline body weight performed on average 11 mins/day more light activity than the10% group at 24 months (p = 0.033) and had significantly lower bouts of InactivityRandomisation to a successful intensive weight loss intervention, including regular physical activity encouragement, was not associated with increased physical activity although sleep parameters improved. Physical activity was greater, and night-time waking reduced in those who maintained10% weight loss at 12 and 24 months. TRIAL REGISTRATION ISRCTN03267836.
Databáze: OpenAIRE