P28. Efficient CD19-positive leukaemia cell lysis mediated by a T cell-recruiting triple body a[19-3-19]
| Autor: | Karl-Peter Hopfner, Nadja C. Fenn, Sarah Wildenhain, Christian B. Schiller, Uwe Jacob, Fuat Oduncu, Claudia C. Roskopf, Todd A. Braciak, Georg H. Fey |
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| Rok vydání: | 2014 |
| Předmět: |
Pharmacology
Cancer Research Lysis biology business.industry T cell medicine.medical_treatment Immunology Leukaemia cell Cell selectivity CD19 medicine.anatomical_structure Oncology Cancer immunotherapy Poster Presentation biology.protein Cancer research Molecular Medicine Immunology and Allergy Medicine Antibody business |
| Zdroj: | Journal for Immunotherapy of Cancer |
| ISSN: | 2051-1426 |
| DOI: | 10.1186/2051-1426-2-s2-p19 |
| Popis: | Meeting abstracts The design of antibody derivatives with higher tumour cell selectivity is hoped to improve cancer immunotherapy and to decrease side effects. One promising molecular format that we have developed is the triple body. A triple body allows for selective lysis based on its 'dual |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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