Severe Chronic Kidney Disease Is Associated with a Lower Efficiency of Bariatric Surgery
| Autor: | Séverine Ledoux, Blandine Cherifi, Simon Msika, Sophie Cambos, Diana Kadouch, François Vrtovsnik, Rodi Courie, Muriel Coupaye, Ronan Roussel, Anne Boutten, Marie Beslay, Konstantinos Arapis, Michel Marre, Boris Hansel |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Sleeve gastrectomy medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Renal function Bariatric Surgery 030209 endocrinology & metabolism urologic and male genital diseases Severity of Illness Index Body Mass Index 03 medical and health sciences 0302 clinical medicine Weight loss Risk Factors Weight Loss Medicine Humans Obesity Risk factor Renal Insufficiency Chronic Contraindication Retrospective Studies Nutrition and Dietetics business.industry Retrospective cohort study Middle Aged medicine.disease Prognosis female genital diseases and pregnancy complications Surgery Obesity Morbid Transplantation Treatment Outcome 030211 gastroenterology & hepatology Female medicine.symptom business Kidney disease Glomerular Filtration Rate |
| Zdroj: | Obesity surgery. 29(5) |
| ISSN: | 1708-0428 |
| Popis: | Obesity is a risk factor for chronic kidney disease (CKD) and a relative contraindication for renal transplantation. Bariatric surgery (BS) is an option to address this issue but we hypothesize that severe CKD is associated with a loss of efficacy of BS which could justify recommending it at an earlier stage of the CKD.A retrospective study (n = 101 patients) to test primarily for differences in weight loss at 6 and 12 months according to estimated glomerular filtration rate categories (eGFR 30 including patients on dialysis, 30-60, 60-90, and ≥ 90 ml/min/1.73 mIn the first comparison, the multivariate analysis showed a significant positive association between eGFR and weight loss. However, after exclusion of the subgroup of patients with eGFR 30 ml/min/1.73 mThe efficacy of BS was reduced in patients with advanced CKD. These results support early BS in patients with early-to-moderate CKD. |
| Databáze: | OpenAIRE |
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