Nanomedicine in Hepatocellular Carcinoma: A New Frontier in Targeted Cancer Treatment

Autor:	Anita Bakrania, Gang Zheng, Mamatha Bhat
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	liver cancer RS1-441 Pharmacy and materia medica nanoparticle Pharmaceutical Science Review hepatocellular carcinoma neoplasms nanomedicine gene therapy digestive system diseases
Zdroj:	Pharmaceutics, Vol 14, Iss 41, p 41 (2022) Pharmaceutics
ISSN:	1999-4923
Popis:	Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death and is associated with a dismal median survival of 2–9 months. The fundamental limitations and ineffectiveness of current HCC treatments have led to the development of a vast range of nanotechnologies with the goal of improving the safety and efficacy of treatment for HCC. Although remarkable success has been achieved in nanomedicine research, there are unique considerations such as molecular heterogeneity and concomitant liver dysfunction that complicate the translation of nanotheranostics in HCC. This review highlights the progress, challenges, and targeting opportunities in HCC nanomedicine based on the growing literature in recent years.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a7ceff2684547da2eb16495b8bc089 https://www.mdpi.com/1999-4923/14/1/41 Zobrazit plný text záznamu