Characterization of Alternanthera mosaic virus and its Coat Protein
| Autor: | Anna A. Mukhamedzhanova, Sergey Chirkov, Nina Rodionova, A. A. Smirnov, M. V. Arkhipenko, Joseph Atabekov, Peter Ivanov, Olga Karpova |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
0303 health sciences
Alternanthera mosaic virus biology viruses 030302 biochemistry & molecular biology triple gene block protein 1 RNA Coat protein virus-like particles biology.organism_classification Virology In vitro Virus Article 3. Good health 03 medical and health sciences Biochemistry Portulaca grandiflora coat protein Phosphorylation translation activation Gene potexviruses 030304 developmental biology |
| Zdroj: | The Open Virology Journal |
| ISSN: | 1874-3579 |
| DOI: | 10.2174/1874357901105010136 |
| Popis: | A new isolate of Alternanthera mosaic virus (AltMV-MU) was purified from Portulaca grandiflora plants. It has been shown that the AltMV-MU coat protein (CP) can be efficiently reassembled in vitro under different conditions into helical RNA-free virus-like particles (VLPs) antigenically related to native virus. The AltMV-MU and VLPs were examined by atomic force and transmission electron microscopies. The encapsidated AltMV-MU RNA is nontranslatable in vitro. However, it can be translationally activated by CP phosphorylation or by binding to the TGB1protein from the virus-coded movement triple gene block. |
| Databáze: | OpenAIRE |
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