Risk of Sprint Fidelis defibrillator lead failure is highly dependent on age

Autor: Elodie Morel, Alina Scridon, Philippe Chevalier, Carine Flys, Emilie Nonin, Nicolas Girerd, Julien Pinot
Rok vydání: 2011
Předmět:
Male
Lead dysfunction
Aging
medicine.medical_specialty
medicine.medical_treatment
Sonde Sprint Fidelis
Kaplan-Meier Estimate
Risk Assessment
Âge
Age Distribution
Age
Risk Factors
Internal medicine
Implantable cardioverter defibrillator
Confidence Intervals
medicine
Humans
Lead (electronics)
Survival analysis
Aged
Proportional Hazards Models
Retrospective Studies
Analysis of Variance
Univariate analysis
Proportional hazards model
business.industry
Hazard ratio
Défibrillateur automatique implantable
Arrhythmias
Cardiac
General Medicine
Middle Aged
Sprint Fidelis
Implantable cardioverter-defibrillator
Confidence interval
Defibrillators
Implantable
Surgery
Sprint
Cardiology
Equipment Failure
Female
Dysfonction de sonde
France
Cardiology and Cardiovascular Medicine
business
Algorithms
Follow-Up Studies
Zdroj: Archives of Cardiovascular Diseases. 104:388-395
ISSN: 1875-2136
Popis: SummaryBackgroundIn 2007, Medtronic Sprint Fidelis defibrillator leads were taken off the market due to a high rate of lead failure. Current data do not allow for risk stratification of patients with regard to lead failure.AimsWe sought to determine predictors of Sprint Fidelis lead failure.MethodsBetween 2004 and 2007, 269 Sprint Fidelis leads were implanted in 258 patients in our centre. Variables associated with lead failure were assessed by the Kaplan-Meier method and a Cox survival model.ResultsDuring a median follow-up of 2.80 years (maximum 5.32), we observed 33 (12.3%) Sprint Fidelis lead failures (5-year survival, 65.6%±7.5%). In univariate analysis, age was the only predictor of lead failure (hazard ratio [HR] for 1-year increase 0.97; 95% confidence interval [CI] 0.95–0.99; p=0.009). Patients aged62.5 years (HR 2.80; CI 1.30–6.02; p=0.009). Survival without Sprint Fidelis lead failure was 55.6%±10.4%) in patients aged62.5 years (9/135 leads). The annual incidence of lead failure in patients aged
Databáze: OpenAIRE
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