Efficacy of radiosynovectomy of the knee in rheumatoid arthritis: Evaluation with magnetic resonance imaging
| Autor: | G. Ríos, J. Ignacio Pijoan, M Calabozo, A Alonso-Ruiz, E Ruiz-Lucea, Fernando Perez-Ruiz, F. Saez, I. Aretxabala |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Gadolinium DTPA medicine.medical_specialty Knee Joint Gadolinium Contrast Media chemistry.chemical_element Radiopharmaceutical agent Injections Intra-Articular Arthritis Rheumatoid Rheumatology Internal medicine medicine Humans Synovial fluid Yttrium Radioisotopes Prospective Studies Prospective cohort study Aged medicine.diagnostic_test business.industry Synovial Membrane Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Treatment Outcome medicine.anatomical_structure chemistry Rheumatoid arthritis Female Radiology Radiopharmaceuticals Synovial membrane business Follow-Up Studies |
| Zdroj: | Clinical Rheumatology. 17:277-281 |
| ISSN: | 1434-9949 0770-3198 |
| DOI: | 10.1007/bf01451005 |
| Popis: | The intra-articular injection of a radiopharmaceutical agent (radiosynovectomy) produces a reduction of the synovial inflammatory process. The inflammed synovial membrane can be identified with magnetic resonance imaging after the intravenous administration of gadolinium (MRI-Gd). A 6-month prospective study was carried out in 10 patients with rheumatoid arthritis after radiosynovectomy of the knee. The efficacy was evaluated with clinical parameters and MRI-Gd. A progressive amelioration of synovial effusion, pain, articular range of mobility, total leucocytes count in synovial fluid and synovial membrane thickness through MRI-Gd was observed. The global efficacy was considered to be good in six patients, fair in three and bad in one. The study shows for the first time that MRI-Gd allows the evaluation of the response of the synovial membrane to radiosynovectomy. |
| Databáze: | OpenAIRE |
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