| Autor: |
Nnanyelugo G. Odezulu, Yvette W. Lowney, Kenneth M. Portier, Marianne Kozuch, Allan R. Bacon, Stephen M. Roberts, Leah D. Stuchal |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Journal of toxicology and environmental health. Part A. 85(13) |
| ISSN: |
1528-7394 |
| Popis: |
Recent findings indicate that incidental ingestion of soil by humans primarily involves soil particles150 µm, rather than250 µm-sized fraction previously used for most oral bioaccessibility and bioavailability studies. It was postulated that a greater soil surface area in the finer fraction (150 versus250 µm) might increase oral bioaccessibility of arsenic (As) in soil. Bioaccessibility and concentrations of As were compared in150 and250 µm fractions of 18 soil samples from a variety of arsenic-contaminated sites. The two methods used to measure bioaccessibility were compared - EPA Method 1340 and the California Arsenic Bioaccessibility (CAB) method. Arsenic concentrations were nearly the same or higher in the150 fraction compared with250 µm. EPA Method 1340 and the CAB method presented significantly different bioaccessibility results, as well as estimated relative oral bioavailability (RBA) based upon algorithms specific to the methods, but there was no marked difference for150 and250 µm soil fractions within either method. When compared with RBA determined previously for these soil samples |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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