Unenhanced 3D Turbo Spin-Echo MR Angiography of Lower Limbs in Peripheral Arterial Disease: A Comparative Study With Gadolinium-Enhanced MR Angiography
| Autor: | Cristian Gageanu, Chadi Braidy, Louis Boyer, Pascal Chabrot, Amine Habouchi, Abdoulay Dione Diop, Khadim Niang |
|---|---|
| Přispěvatelé: | Image Science for Interventional Techniques (ISIT), Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Centre National de la Recherche Scientifique (CNRS), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), CHU Clermont-Ferrand, SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Arterial disease [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging Gadolinium chemistry.chemical_element Contrast Media 030204 cardiovascular system & hematology Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences Peripheral Arterial Disease 0302 clinical medicine Imaging Three-Dimensional Meglumine Organometallic Compounds Medicine Humans Radiology Nuclear Medicine and imaging Prospective cohort study ComputingMilieux_MISCELLANEOUS Aged Aged 80 and over business.industry Mr angiography Reproducibility of Results General Medicine Fast spin echo Middle Aged medicine.disease Peripheral chemistry Lower Extremity Nephrogenic systemic fibrosis Spin Labels Radiology business [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing Magnetic Resonance Angiography medicine.drug |
| Zdroj: | American Journal of Roentgenology American Journal of Roentgenology, American Roentgen Ray Society, 2013, 200 (5), pp.1145-1150. ⟨10.2214/AJR.12.8730⟩ American Journal of Roentgenology, 2013, 200 (5), pp.1145-1150. ⟨10.2214/AJR.12.8730⟩ |
| ISSN: | 0361-803X 1546-3141 |
| DOI: | 10.2214/AJR.12.8730⟩ |
| Popis: | The purpose of this study was to assess the feasibility and diagnostic performance of an unenhanced MR angiography sequence (Syngo Native Space, Siemens Healthcare) to detect and quantify lower-limb peripheral arterial disease (PAD), with gadolinium-enhanced MR angiography (CE-MRA) as the reference standard.Fifty-one patients known to have lower-limb arteriopathy were included in this prospective study. For every patient, we performed Native sequence and CE-MRA on a 1.5-T system. We evaluated examination duration, image quality, and location, number, and severity of lesions.Examination duration was longer for Native sequence (mean, 39.6 min, vs 10 min for CE-MRA). Image quality was significantly better for CE-MRA, with 92% of images listed as good to excellent for CE-MRA, compared to 53% for Native. Sensitivity, specificity, negative predictive value (NPV), and accuracy of Native were respectively 75%, 95%, 89%, and 88% for all mixed levels; 52%, 97%, 88%, and 87% for aortoiliac level; 87%, 99%, 95%, and 92% for femoropopliteal level; and 82%, 87%, 87%, and 85% for subpopliteal level. If we considered only patients with Leriche and Fontaine stage II arteriopathy, Native results were slightly better, with respective specificities and NPVs of 96% and 91% for all mixed levels; 98% and 90% for aortoiliac level; 98% and 93% for femoropopliteal level; and 91% and 90% for subpopliteal level.Unenhanced MR angiography, cheaper than CE-MRA, showed in our study a good NPV, which suggests its utility as first-line test to screen for PAD, especially in patients at risk of nephrogenic systemic fibrosis. |
| Databáze: | OpenAIRE |
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