Bacitracin versus mupirocin for Staphylococcus aureus nasal colonization
| Autor: | A. Vaghjimal, Larry I. Lutwick, Edward K. Chapnick, Norberto E. Soto, John R. Protic, Annette Stahl-Avicolli |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
Adult Male Staphylococcus aureus Micrococcaceae Epidemiology medicine.drug_class Antibiotics Mupirocin Bacitracin medicine.disease_cause Microbiology Infectious Disease Transmission Professional-to-Patient chemistry.chemical_compound Medicine Humans Colonization Single-Blind Method Prospective Studies Nasal colonization Antibacterial agent Cross Infection Infection Control biology business.industry Staphylococcal Infections biology.organism_classification Anti-Bacterial Agents Nasal Mucosa Infectious Diseases Treatment Outcome chemistry Carrier State Female business medicine.drug |
| Zdroj: | Infection control and hospital epidemiology. 20(5) |
| ISSN: | 0899-823X |
| Popis: | We performed a randomized prospective study of 5-day treatment with topical mupirocin or bacitracin for the elimination ofStaphylococcus aureusnasal colonization in healthcare workers (HCWs). Nasal cultures were obtained from 141 HCWs, 37 (26%) of whom showed Saureus.After 72 to 96 hours of treatment, the organism was eradicated in 15 (94%) of 16 by mupirocin and in 8 (44%) of 18 by bacitracin (P=.0031). Similar efficacy was demonstrated at 30 days. Mupirocin may be more effective than bacitracin for eradication of Saureusin healthy HCWs. |
| Databáze: | OpenAIRE |
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