Evidence of a membrane-bound phospholipase a in rat liver lysosomes
| Autor: | D.F.M.v.d. Wiel, Jan Verhagen, Y.E. Rahman |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
Membrane bound Biophysics Centrifugation Mitochondria Liver Biochemistry Calcium Chloride Centrifugation Density Gradient Methods Animals Molecular Biology chemistry.chemical_classification Carbon Isotopes Phospholipase A Membranes Chemistry Phosphatidylethanolamines Fatty Acids Fatty acid Cell Biology Hydrogen-Ion Concentration Rats Enzyme Activation Membrane Enzyme Liver Phospholipases Rat liver Female Lysosomes |
| Zdroj: | Biochemical and Biophysical Research Communications. 38:670-677 |
| ISSN: | 0006-291X |
| DOI: | 10.1016/0006-291x(70)90633-9 |
| Popis: | A phospholipase a with optimal activity at pH 7.0–8.0 was found in the membranes of rat liver lysosomes. This enzyme is activated by Ca ++ , and is specific for the fatty acid at the 2-position. The presence of this enzyme in lysosomes is not due to mitochondrial contamination. |
| Databáze: | OpenAIRE |
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