Gestational diabetes in a multiethnic population of Spain: Clinical characteristics and perinatal outcomes
| Autor: | Jaume Puig-de Dou, Juan J. Chillarón, María Ángeles López-Vílchez, David Benaiges, Elisa Hernandez-Rivas, Juana A. Flores-Le Roux, Enric Sagarra, Albert Goday, Juan Pedro-Botet, A. Paya |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism Endocrinology Pregnancy Diabetes mellitus Internal Medicine medicine Birth Weight Humans Prospective Studies Prospective cohort study Gynecology Univariate analysis business.industry Infant Newborn General Medicine medicine.disease Pregnancy Complications Gestational diabetes Diabetes Gestational Spain Cohort Gestation Female business Body mass index |
| Zdroj: | Diabetes Research and Clinical Practice. 100:215-221 |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2013.01.030 |
| Popis: | To compare clinical characteristics and perinatal outcomes between immigrant and Spanish women with gestational diabetes mellitus (GDM) in a multiethnic population of Barcelona and to identify factors independently associated with the development of large-for-gestational-age (LGA) infants.Prospective study of women with GDM from five ethnic groups (Caucasian, South-Central Asian, Latin American, East Asian and Moroccan) at a single institution in Barcelona between 2004 and 2011. Maternal, gestational and newborn characteristics were recorded.The cohort included 456 patients. In univariate analyses, Moroccan women had more frequently a pre-gestational body mass index (BMI)25 kg/m(2) (76.4%, P=0.012), while East Asian women had lower BMI (23.41 ± 2.79 kg/m(2), P0.001), less need for insulin therapy (14.3%, P=0.013) and the highest rate of spontaneous labor (69.8%, P=0.014) and eutocic delivery (63.8%, P=0.032). Also, Latin American women had a higher rate of Cesarean section (52.9%, P0.001) and LGA infants (28.6%, P=0.004), and their newborns had lower umbilical cord pH (7.23 ± 0.06, P=0.005) and Apgar scores (9 [4-10], P0.01) and a higher incidence of neonatal hypoglycemia (51.4%, P=0.045). Logistic regression analysis identified pre-gestational BMI (OR: 1.18; 95% CI: 1.09-1.27), pregnancy weight gain (OR: 1.19; 95% CI: 1.1-1.28) and insulin use during gestation (OR: 2.29; 95% CI: 1.09-4.82) as predictors of LGA infants.Significant ethnic differences were found in clinical characteristics and perinatal outcomes of women with GDM. Latin American women had a higher frequency of adverse perinatal outcomes. Pregestational BMI, pregnancy weight gain and insulin use during pregnancy were independent predictors of LGA. |
| Databáze: | OpenAIRE |
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