Rabies surveillance in wild mammals in South of Brazil
| Autor: | Helena Beatriz de Carvalho Ruthner Batista, Karin Correa Sheffer Ferreira, Paulo Michel Roehe, Aline Alves Scarpellini Campos, Marcelo Meller Alievi, Ana Luisa Tartarotti, Paulo Guilherme Carniel Wagner, Fernando Finoketti, Bruna Zafalon-Silva, Raíssa Nunes dos Santos, Andrea de Cassia Rodrigues da Silva, Ana Cláudia Franco, Julio A. Benavides, Ana Paula Guedes Frazzon, Fabio Branco da Silva, André Alberto Witt |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Rabies 040301 veterinary sciences Wildlife Animals Wild medicine.disease_cause Rabies lyssavirus Serology 0403 veterinary science 03 medical and health sciences Chiroptera biology.animal medicine Animals Humans Primate 030304 developmental biology Mammals 0303 health sciences General Veterinary General Immunology and Microbiology biology Rabies virus 04 agricultural and veterinary sciences General Medicine medicine.disease Virology biology.protein Female Sylvatic cycle Antibody Brazil |
| Zdroj: | Transboundary and Emerging Diseases. 67:906-913 |
| ISSN: | 1865-1682 1865-1674 |
| DOI: | 10.1111/tbed.13415 |
| Popis: | The sylvatic cycle of rabies, caused by the Rabies lyssavirus (RABV), is maintained in the American Continent by aerial and terrestrial wild mammals. In this study, we combined passive surveillance of rescued wild animals with active serological surveillance in targeting areas at Rio Grande do Sul State and Santa Catarina State, south of Brazil, where bites of humans by wild animals have been reported. Circulation of RABV in Brazilian bats has been extensively demonstrated; however, the observation of such infections in unvaccinated terrestrial mammals is restricted to some regions of the Brazilian territory. The occurrence of rabies infection in unvaccinated animals has been identified by the detection of RABV antigens in brain tissues of dead animals or anti-rabies antibodies in live animals. Such strategies allow the surveillance of rabies and the assessment of spillover risks from infected animals to humans. Our aim included the identification of species of wild mammals that are involved in the sylvatic cycle of rabies virus in Southern Brazil and to assess the risk of rabies infection in patients bitten by wild animals in the state. To assess the anti-rabies seropositivity, sera were submitted to the Rapid Fluorescent Focus Inhibition Test (RFFIT). Among the 100 mammals tested, five animals were seropositive (5%) including three (one primate and two wild canids) with rabies virus neutralizing antibodies titres >0.5 IU/ml. Our results highlight the exposure to RABV of both primates and wild canids in Southern Brazil and suggest the occurrence of RABV exposure without the development of further symptoms. Further research should clarify the dynamics of rabies in wild canids and whether primates are accidental hosts or reservoirs for RABV at this region. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|