Treatment of Chronic Renal Failure by Transplantation and Disalysis
Autor: | Richard Wilson, Nicholas L. Tilney, Edward B. Hager, C M Boyden, G W Sandberg |
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Rok vydání: | 1975 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Postoperative Complications Pregnancy Renal Dialysis Allograft survival Humans Transplantation Homologous Medicine In patient Dialysis business.industry Incidence (epidemiology) Twins Monozygotic Work rehabilitation Kidney Transplantation Tissue Donors Surgery Transplantation Transplantation Isogeneic surgical procedures operative Quality of Life Kidney Failure Chronic Chronic renal failure Female business Research Article |
Zdroj: | Annals of Surgery. 182:108-115 |
ISSN: | 0003-4932 |
DOI: | 10.1097/00000658-197508000-00004 |
Popis: | The overall transplant experience at the Peter Bent Brigham Hospital which extends over twenty years has been reviewed; the course of all patients was updated to a followup of at least one year (through October 1973). A total of 388 patients received 427 renal isografts and allografts between March 1951 and October 1972. Of these, 58% were still alive at the end of the followup period, 50% with a functioning graft. The results of patient and allograft survival early (1959-1968) and later (1968-1973) in the experience have been compared. The significant decline in patient mortality, especially among recipients of cadaver allografts, demonstrates improved treatment of complications and increased availability of dialysis. The improvement of allograft function during the two time periods is less striking but still significant. Overall social and work rehabilitation following transplantation was evaluated in 284 patients, 86% of whom became at least as well adjusted as they had been prior to the development of renal failure. The incidence and individual causes for mortality and complications of transplantation have been compared to results from the National Dialysis Registry, figures comparable to those of the dialysis program at this institution. Transplantation and dialysis must be used conjointly and in a complimentary manner as part of the total treatment for those with end-stage renal failure. |
Databáze: | OpenAIRE |
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